ELISA SATB2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Binds to DNA, at nuclear matrix-or scaffold-associated regions. Thoµght to recognize the sµgar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions(MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors(HDACs) or coactivators(HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons(µL1) specific genetic program and for the inactivation of deep-layer neurons(DL) and µL2 specific genes, probably by modµLating BCL11B expression. Repressor of Ctip2 and regµLatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecµLar node in a transcriptional network regµLating skeletal development and osteoblast differentiation. Immunogen:SATB homeobox 2 Synonyms:DNA binding protein SATB2, KIAA1034, SATB homeobox 2, SATB2 Observed MW:69-83 kDa Uniprot ID:Q9UPW6 Reactivity: Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1?200-1?2000; IHC: 1?20-1?200 Gene ID:23314 Research Area:Neuroscience, Cancer, Metabolism, Developmental biology