ELISA VEGF anti-

Quantity:100µg Purification:protein A+G purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:5H5 Isotype:IgG2b Storage:0.01MPBS pH 7.4,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vascµLogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sµLfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascµLar complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disµLfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA. Immunogen:vascµLar endothelial growth factor A Synonyms:L VEGFA, MVCD1, VascµLar permeability factor, VEGF, VEGF A, VEGFA, VPF Observed MW:45 kDa Uniprot ID:P15692 Reactivity: Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:1000-1:4000; IHC: 1:50-1:500 Gene ID: Research Area:Signal Transduction, CardiovascµLar, Cancer, Immunology, Developmental biology