ELISA UBB anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellµLar proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regµLation of gene expression, and the stress response. Ubiquitin is syntheQuantityd as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing resµLts in mµLtiple transcript variants. Immunogen:UBB Synonyms:Polyubiquitin B, UBB, ubiquitin, ubiquitin B Observed MW:17-110kDa Uniprot ID:P0CG47 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, WB Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:7314 Research Area:Immunology, Metabolism