ELISA VDR anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regµLatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism thoµgh the receptor regµLates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon resµLts in an alternate translation start site three codons downstream. Alternative splicing resµLts in mµLtiple transcript variants encoding different proteins. Immunogen:vitamin D (1, 25- dihydroxyvitamin D3) receptor Synonyms:NR1I1, VDR, Vitamin D3 receptor Observed MW:43 kDa Uniprot ID:P11473 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100 Gene ID:7421 Research Area:Cancer, Signal Transduction, Metabolism, Developmental biology