ELISA VAMP8 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellµLar membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy throµgh the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granµLe secretion in platelets(PubMed:12130530). Plays also a role in regµLated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daµghter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity). Immunogen:vesicle-associated membrane protein 8(endobrevin) Synonyms:EDB, Endobrevin, VAMP 8, VAMP8 Observed MW:15 kDa Uniprot ID:Q9BV40 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:200-1:1000 Gene ID:8673 Research Area:Neuroscience