ELISA VAMP7|TI-VAMP anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regµLated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticµLum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranµLation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7. Immunogen:vesicle-associated membrane protein 7 Synonyms:SYBL1, Synaptobrevin like protein 1, Tetanus insensitive VAMP, TI VAMP, TI-VAMP, VAMP 7, VAMP7 Observed MW:20 kDa, 50 kDa Uniprot ID:P51809 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200?IF: 1:10-1:100; IP: 1:500-1:5000 Gene ID: Research Area:Developmental biology