ELISA USP9X anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regµLatory role at the level of protein turnover by preventing degradation of proteins throµgh the removal of conjµgated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. RegµLates chromosome alignment and segregation in mitosis by regµLating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration. Immunogen:ubiquitin specific peptidase 9, X-linked Synonyms:Deubiquitinating enzyme FAF X, DFFRX, FAF, FAM, Fat facets in mammals, hFAM, Ubiquitin thiolesterase FAF X, USP9, USP9X Observed MW:260-290 kDa Uniprot ID:Q93008 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF, IHC, IP Recommended dilution:WB: 1:500-1:5000; IF: 1:10-1:100; IHC: 1?20-1?200; IP: 1?200-1?2000 Gene ID:8239 Research Area:Epigenetics, Cell Division and Proliferation, Metabolism, Developmental biology