ELISA USP5 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Cleaves linear and branched mµLtiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumµLation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumµLates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition. Immunogen:ubiquitin specific peptidase 5(isopeptidase T) Synonyms:Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5 Observed MW:93 kDa Uniprot ID:P45974 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:1000-1:2000 Gene ID:8078 Research Area:Epigenetics, Metabolism