ELISA USP44 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Deubiquitinase that plays a key regµLatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regµLator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regµLator of histone H2B(H2BK120ub1) ubiquitination. Immunogen:ubiquitin specific peptidase 44 Synonyms:Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44 Observed MW:81 kDa Uniprot ID:Q9H0E7 Reactivity: Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:5000 Gene ID:84101 Research Area:Epigenetics, Metabolism