ELISA Uromodulin anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:UromodµLin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. UromodµLin is syntheQuantityd by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubµLe. UromodµLin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodµLin lead to rare autosomal dominant diseases, collectively referred to as uromodµLin-associated kidney diseases.(PMID: 21654721) Immunogen:uromodµLin Synonyms:ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, UMOD, uromodµLin Observed MW:55-70 kDa Uniprot ID:P07911 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:500; IP: 1:200-1:2000 Gene ID: Research Area: