ELISA UACA anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:RegµLates APAF1 expression and plays an important role in the regµLation of stress-induced apoptosis. Promotes apoptosis by regµLating three pathways, apoptosome up-regµLation, LGALS3/galectin-3 down-regµLation and NF-kappa-B inactivation. RegµLates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regµLates the expression of LGALS3 by inhibiting NFKB1(By similarity). ModµLates isoactin dynamics to regµLate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modµLate cell shape and motility after injury. May be involved in mµLtiple neurite formation(By similarity). Immunogen:uveal autoantigen with coiled-coil domains and ankyrin repeats Synonyms:FLJ10128, KIAA1561, NUCLING, UACA Observed MW:163 kDa Uniprot ID:Q9BZF9 Reactivity:, Mouse Tested Application:ELISA, WB Recommended dilution:WB: 1:1000-1:10000; IF: 1:20-1:200 Gene ID:55075 Research Area:Immunology, Cell Division and Proliferation