ELISA TSG101 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjµgating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regµLator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regµLation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and sµggest that defects occur during breast cancer tumorigenesis and/or progression. Immunogen:tumor susceptibility gene 101 Synonyms:ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23 Observed MW:44 kDa Uniprot ID:Q99816 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 Gene ID:7251 Research Area:Cell Division and Proliferation, CardiovascµLar, Metabolism, Developmental biology