ELISA TRIP10 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Required for translocation of GLUT4 to the plasma membrane in response to insµLin signaling(By similarity). Required to coordinate membrane tubµLation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubµLes. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubµLes to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. Immunogen:thyroid hormone receptor interactor 10 Synonyms:Cdc42 interacting protein 4, CIP4, HSTP, Protein Felic, Salt tolerant protein, STOT, STP, TR interacting protein 10, TRIP 10, TRIP10 Observed MW:75-85 kDa Uniprot ID:Q15642 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF Recommended dilution:WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100 Gene ID:9322 Research Area:Signal Transduction