ELISA TRIB3 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Disrupts insµLin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regµLates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
Immunogen:tribbles homolog 3(Drosophila)
Synonyms: C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3
Observed MW:42 kDa
Uniprot ID:Q96RU7
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IP
Recommended dilution:WB: 1:500-1:5000; IP: 1:200-1:2000
Gene ID:57761
Research Area:Signal Transduction, Metabolism
Internal Reference:
FNab08966
Website URL:
/shop/fnab08966-elisa-trib3-anti-178540
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