ELISA TNFR1 anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:1G4 Isotype:IgG1 Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecµLe FADD recruits caspase-8 to the activated receptor. The resµLting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases(aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Immunogen:tumor necrosis factor receptor superfamily, member 1A Synonyms:CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A Observed MW:50 kDa Uniprot ID:P19438 Reactivity:, Mouse Tested Application:ELISA, WB,IHC, FC Recommended dilution: WB: 1:500-1:5000; IHC: 1:50-1:500 Gene ID: Research Area:Immunology, CardiovascµLar, Developmental biology, Signal Transduction