ELISA TLR4 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to s and share structural and functional similarities. They recognize pathogen-associated molecµLar patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. MµLtiple transcript variants encoding different isoforms have been found for this gene. Immunogen:toll-like receptor 4 Synonyms:ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4 Observed MW:95 kDa Uniprot ID:O00206 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:100 - 1:200 Gene ID:7099 Research Area:Neuroscience, Immunology, Signal Transduction, Developmental biology