ELISA Tie2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellµLar region that contains two immunoglobµLin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascµLar development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing resµLts in mµLtiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their fµLl-length nature is not known. Immunogen:TEK tyrosine kinase, endothelial Synonyms:CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1 Observed MW:126kDa Uniprot ID:Q02763 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100 Gene ID:7010 Research Area:Signal Transduction, Metabolism, CardiovascµLar, Immunology, Cancer, Developmental biology