ELISA TBC1D5 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN); the function seems to require its catalytic activity. Involved in regµLation of autophagy(PubMed:22354992). May act as a molecµLar switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regµLate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes(PubMed:24603492). Immunogen:TBC1 domain family, member 5 Synonyms:KIAA0210 Observed MW:89 kDa Uniprot ID:Q92609 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IP Recommended dilution:WB: 1:500-1:2400; IP: 1:200-1:1000 ; IHC: 1:20-1:200 Gene ID:9779 Research Area:Cancer