ELISA SYNE2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:MµLti-isomeric modµLar protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellµLar spatial organization. Component of SUN-protein-containing mµLtivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear(TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for centrosome migration to the apical cell surface during early ciliogenesis. Immunogen:spectrin repeat containing, nuclear envelope 2 Synonyms:KIAA1011, NUA Observed MW:55 kDa Uniprot ID:Q8WXH0 Reactivity: Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:1000 Gene ID:23224 Research Area:Signal Transduction