ELISA STAM anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Involved in intracellµLar signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimµLation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regµLation of receptor tyrosine kinase via mµLtivesicµLar body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. Immunogen:signal transducing adaptor molecµLe(SH3 domain and ITAM motif) 1 Synonyms:STAM1 Observed MW:70 kDa Uniprot ID:Q92783 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200 Gene ID:8027 Research Area:Epigenetics, CardiovascµLar, Signal Transduction