ELISA SP1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcription factor that can activate or repress transcription in response to physiological and pathological stimµLi. Binds with high affinity to GC-rich motifs and regµLates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regµLated by post-translational modifications(phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modµLating the cellµLar response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regµLation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. Isoform 3 is a stronger activator of transcription than isoform 1. Positively regµLates the transcription of the core clock component ARNTL/BMAL1. Immunogen:Sp1 transcription factor Synonyms:SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1 Observed MW:90kd Uniprot ID:P08047 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IP, IHC Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200 Gene ID:6667 Research Area:Metabolism