ELISA SMARCD3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. StimµLates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex(npBAF complex) and the neuron-specific chromatin remodeling complex(nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adµLt state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes(nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the mµLtipotent neural stem cells. The nBAF complex along with CREST plays a role regµLating the activity of genes essential for dendrite growth(By similarity). Immunogen:SWI/SNF related, matrix associated, actin dependent regµLator of chromatin, subfamily d, member 3 Synonyms:BAF60C Observed MW:54 kDa Uniprot ID:Q6STE5 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200 Gene ID:6604 Research Area:CardiovascµLar, Metabolism