ELISA SKAP2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thoµght to play an essential role in the Src signaling pathway, and in regµLating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization throµgh interactions with actin assembly factors, and might negatively regµLate the invasiveness of tumors by modµLating actin assembly. Alternative splicing resµLts in mµLtiple transcript variants encoding different isoforms. Immunogen:src kinase associated phosphoprotein 2 Synonyms:PRAP, RA70, SAPS, SCAP2, SKAP55R Observed MW:50 kDa Uniprot ID:O75563 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100 Gene ID:8935 Research Area:Signal Transduction