ELISA SH3BP4 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:May function in transferrin receptor internalization at the plasma membrane throµgh a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regµLator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regµLate cell growth, proliferation and autophagy. Immunogen:SH3-domain binding protein 4 Synonyms:BOG25, EHB10, TTP Observed MW:120 kDa Uniprot ID:Q9P0V3 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IF, IP Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200 Gene ID:23677 Research Area:Cancer, Signal Transduction, Metabolism, Developmental biology