ELISA Phospho-FOXO3 (S253) anti-

Quantity :50µL Clone Number:1E1 Aliases:Forkhead box protein O3, AF6q21 protein, FOXO3 Product Type:Recombinant Antibody Immunogen Species: UniProt ID:O43524 Immunogen:A syntheQuantityd peptide derived from Phospho-FOXO3 (S253) Raised in: Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 Background:Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regµLation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regµLators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FOXO3 Research Areas:Epigenetics and Nuclear Signaling