ELISA TRIM25 anti-

Quantity :100µL Clone Number: Aliases:E3 ubiquitin/ISG15 ligase TRIM25 antibody; EFP antibody; Estrogen responsive finger protein antibody; Estrogen-responsive finger protein antibody; RING finger protein 147 antibody; RNF 147 antibody; RNF147 antibody; TRI25 antibody; TRI25_ antibody; TRIM 25 antibody; Trim25 antibody; Tripartite motif containing 25 antibody; Tripartite motif containing protein 25 antibody; Tripartite motif protein TRIM25 antibody; Tripartite motif-containing protein 25 antibody; Tripartite motifcontaining25 antibody; Ubiquitin/ISG15-conjµgating enzyme TRIM25 antibody; Z147 antibody; Zinc finger protein 147 (estrogen responsive finger protein) antibody; Zinc finger protein 147 antibody; Zinc finger protein-147 antibody; ZNF 147 antibody; ZNF147 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14258 Immunogen:SyntheQuantityd peptide derived from internal of ZNF147. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regµLation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Inoue S., Proc. Natl. Acad. Sci. U.S.A. 90:11117-11121(1993). The MGC Project Team, Genome Res. 14:2121-2127(2004). Rush J., Nat. Biotechnol. 23:94-101(2005). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TRIM25 Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Signal transduction