ELISA Phospho-BCAR1 (Tyr410) anti-

Quantity :100µL Clone Number: Aliases:BCAR 1 antibody; Bcar1 antibody; BCAR1_ antibody; Breast cancer anti estrogen resistance 1 antibody; Breast cancer anti estrogen resistance 1 protein antibody; Breast cancer anti-estrogen resistance protein 1 antibody; CAS antibody; Cas scaffolding protein family member 1 antibody; CAS1 antibody; Cass1 antibody; Crk associated substrate antibody; Crk associated substrate p130Cas antibody; CRK-associated substrate antibody; CRKAS antibody; FLJ12176 antibody; FLJ45059 antibody; p130cas antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P56945 Immunogen:Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from p130 Cas Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100 Background: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells. Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535. Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863. Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189. Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCAR1 Research Areas:Cancer;Signal transduction