ELISA Phospho-CSF1R (Tyr561) anti-

Quantity :100µL Clone Number: Aliases:C FMS antibody; CD 115 antibody; CD115 antibody; CD115 antigen antibody; CFMS antibody; Colony stimµLating factor 1 receptor antibody; Colony stimµLating factor I receptor antibody; CSF 1 R antibody; CSF 1R antibody; CSF-1 receptor antibody; CSF-1-R antibody; CSF1 R antibody; CSF1R antibody; CSF1R_ antibody; CSFR antibody; EC 2.7.10.1 antibody; FIM 2 antibody; FIM2 antibody; FMS antibody; FMS proto oncogene antibody; FMS protooncogene antibody; HDLS antibody; M-CSF Receptor antibody; M-CSF-R antibody; Macrophage colony stimµLating factor 1 receptor antibody; Macrophage colony stimµLating factor I receptor antibody; Macrophage colony-stimµLating factor 1 receptor antibody; McDonoµgh feline sarcoma viral (v fms) oncogene homolog antibody; MCSFR antibody; Oncogen FMS antibody; Proto-oncogene c-Fms antibody; V-FMS McDonoµgh feline sarcoma viral oncogen homolog; formerly antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P07333 Immunogen:Peptide sequence around phosphorylation site of tyrosine 561 (N-S-Y(p)-T-F) derived from CSFR Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100 Background: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regµLation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regµLation of osteoclast proliferation and differentiation, the regµLation of bone resorption, and is required for normal bone and tooth development. Hampe A., Oncogene Res. 4:9-17(1989). Andre C., Genomics 39:216-226(1997). Liu T., J. Proteome Res. 4:2070-2080(2005). Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CSF1R Research Areas:CardiovascµLar;Immunology;Signal transduction