ELISA ACTN1 anti-

Quantity :50µL Clone Number: Aliases:actinin 1 smooth muscle antibody; Actinin alpha 1 antibody; actinin; alpha 1 antibody; ACTN 1 antibody; Actn1 antibody; ACTN1_ antibody; Alpha Actinin 1 antibody; Alpha actinin cytoskeletal isoform antibody; Alpha-actinin cytoskeletal isoform antibody; Alpha-actinin-1 antibody; BDPLT15 antibody; F actin cross linking protein antibody; F-actin cross-linking protein antibody; FLJ40884 antibody; FLJ54432 antibody; Non muscle alpha actinin 1 antibody; Non-muscle alpha-actinin-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P12814 Immunogen:Fusion protein of ACTN1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:15-1:50 Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with mµLtiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ACTN1 Research Areas:Developmental biology;Signal transduction?Stem cells