ELISA SSX2IP anti-

Quantity :50µg Clone Number: Aliases:ADIP antibody; ADIP_ antibody; Afadin and alpha actinin binding protein antibody; Afadin DIL domain interacting protein antibody; Afadin DIL domain-interacting protein antibody; Afadin- and alpha-actinin-binding protein antibody; FLJ10848 antibody; KIAA0923 antibody; MGC75026 antibody; OTTHUMP00000011574 antibody; SSX 2 interacting protein antibody; SSX2 interacting protein antibody; SSX2-interacting protein antibody; SSX2IP antibody; Synovial sarcoma X breakpoint 2 interacting protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y2D8 Immunogen:Recombinant Afadin- and alpha-actinin-binding protein (485-614AA) Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 Background:Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system throµgh alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs throµgh afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubµLe nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regµLator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SSX2IP Research Areas:Tags & Cell Markers; Signal transduction