ELISA SPO11 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Cancer/testis antigen 35 antibody; CT35 antibody; Meiotic recombination protein SPO 11 antibody; Meiotic recombination protein SPO11 antibody; MGC39953 antibody; SPATA43 antibody; Spermatogenesis associated 43 antibody; SPO 11 antibody; SPO11 antibody; SPO11 meiotic protein covalently bound to DSB antibody; SPO11 meiotic protein covalently bound to DSB homolog antibody; SPO11 meiotic protein covalently bound to DSB like antibody; SPO11_ antibody; TOPVIA antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y5K1 Immunogen:Recombinant Meiotic recombination protein SPO11 protein (28-109AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation throµgh cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SPO11 Research Areas:Epigenetics and Nuclear Signaling; Cell biology