ELISA L3MBTL1 anti-

Quantity :50µL Clone Number: Aliases:dJ138B7.3 antibody; H-L(3)MBT antibody; H-l(3)mbt protein antibody; KIAA0681 antibody; L(3)mbt protein homolog antibody; L(3)mbt-like antibody; L3MBT antibody; L3MBTL antibody; L3MBTL1 antibody; Lethal (3) malignant brain tumor l(3 antibody; Lethal(3)malignant brain tumor-like protein 1 antibody; LMBL1_ antibody; RGD1307316 antibody; ZC2HC3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y468 Immunogen:Recombinant Lethal(3)malignant brain tumor-like protein 1 protein (513-752AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a \\\'reader\\\' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at \\\'Lys-26\\\' (H1bK26me1 and H1bK26me2) and histone H4 at \\\'Lys-20\\\' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at \\\'Lys-382\\\', leading to repress p53/TP53-target genes. Also recognizes and binds RB1/RB monomethylated at \\\'Lys-860\\\'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces mµLtinucleated cells, sµggesting that it is required to accomplish normal mitosis. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:L3MBTL1 Research Areas:Epigenetics and Nuclear Signaling