ELISA SBNO2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y2G9 Immunogen:Recombinant Protein strawberry notch homolog 2 protein (6-146AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as a transcriptional coregµLator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regµLator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regµLation of osteoblast differentiation (By similarity). Involved in the transcriptional corepression of NF-kappaB in macrophages (PubMed:18025162). Plays a role as a regµLator in the proinflammatory cascade (PubMed:18025162). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SBNO2 Research Areas:Epigenetics and Nuclear Signaling; Immunology