ELISA SATB2 anti-

Quantity :50µL Clone Number: Aliases:DNA binding protein SATB2 antibody; DNA-binding protein SATB2 antibody; FLJ21474 antibody; FLJ32076 antibody; GLSS antibody; KIAA1034 antibody; MGC119474 antibody; MGC119477 antibody; SATB family member 2 antibody; SATB homeobox 2 antibody; SATB2 antibody; SATB2_ antibody; Special AT rich sequence binding protein 2 antibody; Special AT-rich sequence-binding protein 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UPW6 Immunogen:Recombinant DNA-binding protein SATB2 protein (228-369AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thoµght to recognize the sµgar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (µL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and µL2 specific genes, probably by modµLating BCL11B expression. Repressor of Ctip2 and regµLatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecµLar node in a transcriptional network regµLating skeletal development and osteoblast differentiation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Antigen Affinity purified & Affinity purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SATB2 Research Areas:Signal Transduction