ELISA SENP1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:SENP 1 antibody; SENP1 antibody; SENP1_ antibody; Sentrin specific protease 1 antibody; Sentrin-specific protease 1 antibody; Sentrin/SUMO specific protease 1 antibody; Sentrin/SUMO specific protease antibody; Sentrin/SUMO specific protease SENP 1 antibody; Sentrin/SUMO specific protease SENP1 antibody; Sentrin/SUMO-specific protease SENP1 antibody; SUMO1/sentrin specific peptidase 1 antibody; SUMO1/sentrin specific protease 1 antibody; SuPr 2 antibody; SuPr2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9P0U3 Immunogen:Recombinant Sentrin-specific protease 1 protein (63-214AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Protease that catalyzes two essential functions in the SUMO pathway: processing of fµLl-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjµgation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjµgates SUMO1 from HIPK2. Deconjµgates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjµgates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjµgates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SENP1 Research Areas:Epigenetics and Nuclear Signaling; Cell biology