ELISA POLR3F anti-

Quantity :50µg Clone Number: Aliases:DNA directed RNA polymerase III 39 kDa polypeptide antibody; DNA directed RNA polymerase III 39 kDa polypeptide F antibody; DNA directed RNA polymerase III subunit F antibody; DNA directed RNA polymerase III subunit RPC6 antibody; DNA directed RNA polymerases III 39 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit F antibody; DNA-directed RNA polymerase III subunit RPC6 antibody; MGC13517 antibody; Polr3f antibody; Polymerase (RNA) III (DNA directed) polypeptide F antibody; RNA polymerase III 39 kDa subunit antibody; RNA polymerase III C39 subunit antibody; RNA polymerase III subunit C6 antibody; RPC 39 antibody; RPC 6 antibody; RPC39 antibody; RPC6 antibody; RPC6_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H1D9 Immunogen:Recombinant DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000 Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which syntheQuantitys small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellµLar bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B throµgh the RIG-I pathway. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:POLR3F Research Areas:Epigenetics and Nuclear Signaling