ELISA FLRT3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:fibronectin leucine rich transmembrane protein 3 antibody; Fibronectin-like domain-containing leucine-rich transmembrane protein 3 antibody; FLRT 3 antibody; FLRT3 antibody; FLRT3_ antibody; KIAA1469 antibody; Leucine-rich repeat transmembrane protein FLRT3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NZU0 Immunogen:Recombinant Leucine-rich repeat transmembrane protein FLRT3 protein (209-264AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repµLsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascµLar development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellµLar domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repµLsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed:14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regµLation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FLRT3 Research Areas:Cancer; Developmental biology; Signal transduction