ELISA UXT anti-

Quantity :50µL Clone Number: Aliases:Androgen receptor trapped clone 27 protein antibody; ART 27 antibody; ART-27 antibody; OTTHUMP00000023226 antibody; OTTHUMP00000023227 antibody; Protein UXT antibody; SKP2 associated alpha PFD 1 antibody; STAP1 antibody; Ubiquitously expressed prefoldin like chaperone antibody; Ubiquitously expressed transcript antibody; Ubiquitously expressed transcript protein antibody; Uxt antibody; UXT_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UBK9 Immunogen:Recombinant Protein UXT protein (1-157AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Involved in gene transcription regµLation. Acts in concert with the corepressor URI1 to regµLate androgen receptor transcription (AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation (PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a mµLtidomain organizer that potentially integrates mitochondria and the microtubµLar cytoskeleton with chromosome remodeling (PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially throµgh its association with LRPPRC (PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function (PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimµLatory factors like MECOM (PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UXT Research Areas:Epigenetics and Nuclear Signaling; Cancer; Signal transduction