ELISA CHMP5 Antibody, HRP

Quantity :50µg Clone Number: Aliases:apoptosis-related protein PNAS-2 antibody; C9orf83 antibody; CGI 34 antibody; Charged mµLtivesicµLar body protein 5 antibody; CHMP 5 antibody; CHMP family; member 5 antibody; chmp5 antibody; CHMP5_ antibody; Chromatin modifying protein 5 antibody; Chromatin-modifying protein 5 antibody; Chromosome 9 open reading frame 83 antibody; HGNC:26942 antibody; HSPC177 antibody; hVps60 antibody; PNAS 2 antibody; SNF7 domain containing protein 2 antibody; SNF7 domain-containing protein 2 antibody; SNF7DC2 antibody; Vacuolar protein sorting 60 antibody; Vacuolar protein sorting-associated protein 60 antibody; Vps60 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NZZ3 Immunogen:Recombinant Charged mµLtivesicµLar body protein 5 protein (1-219AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in mµLtivesicµLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimµLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CHMP5 Research Areas:Signal transduction