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ELISA SLC27A5 anti-

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Quantity :100µL Clone Number: Aliases:ACSB antibody; ACSVL6 antibody; BA CoA ligase antibody; BA-CoA ligase antibody; BACS antibody; BAL antibody; Bile acid CoA ligase antibody; Bile acid-CoA ligase antibody; Bile acyl CoA synthetase antibody; Bile acyl-CoA synthetase antibody; Cholate CoA ligase antibody; Cholate--CoA ligase antibody; FACVL3 antibody; FATP 5 antibody; FATP-5 antibody; FATP5 antibody; Fatty acid Coenzyme A ligase very long chain 3 antibody; Fatty acid transport protein 5 antibody; Fatty-acid-coenzyme A ligase antibody; FLJ22987 antibody; S27A5_ antibody; Slc27a5 antibody; Solute carrier family 27 (fatty acid transporter) member 5 antibody; Solute carrier family 27 member 5 antibody; Very long chain acyl CoA synthetase homolog 2 antibody; Very long chain acyl CoA synthetase related protein antibody; very long-chain 3 antibody; Very long-chain acyl-CoA synthetase homolog 2 antibody; Very long-chain acyl-CoA synthetase-related protein antibody; VLACS related antibody; VLACS-related antibody; VLACSR antibody; VLCS H2 antibody; VLCS-H2 antibody; VLCSH2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y2P5 Immunogen:SyntheQuantityd peptide derived from internal of SLC27A5. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 Background:Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjµgation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canalicµLi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circµLation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Steinberg S.J., Mol. Genet. Metab. 68:32-42(1999). Steinberg S.J., J. Biol. Chem. 275:15605-15608(2000). Mihalik S.J., J. Biol. Chem. 277:24771-24779(2002). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC27A5 Research Areas:Cancer?CardiovascµLar;Metabolism;Signal transduction

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