ELISA TCHP Antibody, HRP

Quantity :50µg Clone Number: Aliases:TCHP antibody; Trichoplein keratin filament-binding protein antibody; Protein TCHP antibody; Mitochondrial protein with oncostatic activity antibody; Mitostatin antibody; Tumor suppressor protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BT92 Immunogen:Recombinant Trichoplein keratin filament-binding protein (1-498AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regµLation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regµLate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regµLator of ciliogenesis (PubMed:25270598). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TCHP Research Areas:Others