ELISA Phospho-CDH5 (Tyr731) anti-

Quantity :100µL Clone Number: Aliases:7B 4 antibody; 7B4 antibody; 7B4 antigen antibody; CADH5_ antibody; Cadherin 5 antibody; Cadherin 5 type 2 antibody; Cadherin 5, type 2 (vascµLar endothelium) antibody; Cadherin 5, type 2, VE cadherin (vascµLar epithelium) antibody; cadherin, vascµLar endothelial antibody; cadherin, vascµLar endothelial, 1 antibody; Cadherin-5 antibody; Cadherin5 antibody; CD 144 antibody; CD144 antibody; CD144 antigen antibody; CDH 5 antibody; CDH5 antibody; CDH5 protein antibody; Endothelial specific cadherin antibody; FLJ17376 antibody; OTTHUMP00000174777 antibody; VascµLar endothelial cadherin antibody; VascµLar epithelium cadherin antibody; VE Cad antibody; VE-cadherin antibody; VEC antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P33151 Immunogen:Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from VE-Cadherin. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:1000 Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology throµgh control of the cohesion and organization of the intercellµLar junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascµLar lumen. Wessel F, et al. (2014) Nat Immunol 15, 223-30 Sawada J, et al. (2012) Cancer Cell 22, 235-49 Turowski P, et al. (2008) J Cell Sci 121, 29-37 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDH5 Research Areas:Cancer?CardiovascµLar;Signal transduction