ELISA NAT10 Antibody, HRP

Quantity :50µg Clone Number: Aliases:ALP antibody; DKFZp434C116 antibody; FLJ10774 antibody; FLJ12179 antibody; FLJ23850 antibody; hALP antibody; KIAA1709 antibody; N acetyltransferase 10 antibody; N acetyltransferase 10 GCN5 related antibody; N acetyltransferase like antibody; N acetyltransferase like protein antibody; N-acetyltransferase 10 antibody; NAT10 antibody; NAT10_ antibody; NET43 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H0A0 Immunogen:Recombinant RNA cytidine acetyltransferase protein (909-1025AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for fµLl tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167). Can acetylate both histones and microtubµLes. Histone acetylation may regµLate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimµLating the transcription of TERT, and may also regµLate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubµLin, which may affect microtubµLe stability and cell division (PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NAT10 Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Signal transduction