ELISA TEAD3 anti-

Quantity :50µg Clone Number: Aliases:DTEF 1 antibody; DTEF-1 antibody; DTEF1 antibody; ETFR 1 antibody; ETFR1 antibody; TEA domain family member 3 antibody; TEA domain family member 5 antibody; TEAD 3 antibody; TEAD-3 antibody; Tead3 antibody; TEAD3_ antibody; TEAD5 antibody; TEF 5 antibody; TEF5 antibody; Transcriptional enhancer factor 5 antibody; Transcriptional enhancer factor TEF 5 (DTEF 1) antibody; Transcriptional enhancer factor TEF 5 antibody; Transcriptional enhancer factor TEF-5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99594 Immunogen:Recombinant Transcriptional enhancer factor TEF-5 protein (112-435AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:500-1:1000 Background:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ Quantity control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regµLatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regµLatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regµLating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to mµLtiple functional elements of the chorionic somatomammotropin-B gene enhancer. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TEAD3 Research Areas:Epigenetics and Nuclear Signaling; Developmental biology