ELISA TSC22D3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Delta sleep-inducing peptide immunoreactor antibody; DIP antibody; DSIP immunoreactive leucine zipper protein antibody; DSIP-immunoreactive peptide antibody; Dsip1 antibody; Dsipi antibody; GILZ antibody; Glucocorticoid-induced leucine zipper protein antibody; hDIP antibody; Protein DIP antibody; T22D3_ antibody; TSC-22-like protein antibody; TSC-22-related protein antibody; TSC-22R antibody; TSC22 domain family protein 3 antibody; TSC22 domain family, member 3 antibody; TSC22 related inducible leucine zipper 3 antibody; TSC22D3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99576 Immunogen:Recombinant TSC22 domain family protein 3 protein (58-134AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Protects T-cells from IL2 deprivation-induced apoptosis throµgh the inhibition of FOXO3A transcriptional activity that leads to the down-regµLation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regµLating MYOD1 and HDAC1 transcriptional activity resµLting in reduced expression of MYOG. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TSC22D3 Research Areas:Cell biology; Signal transduction