ELISA VPS52 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:VPS52 antibody; SACM2LVacuolar protein sorting-associated protein 52 homolog antibody; SAC2 suppressor of actin mutations 2-like protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N1B4 Immunogen:Recombinant Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:VPS52 Research Areas:Signal transduction