ELISA TSC1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Hamartin antibody; kiaa0243 antibody; LAM antibody; TSC antibody; Tsc1 antibody; Tsc1 gene antibody; TSC1_ antibody; Tuberous sclerosis 1 antibody; Tuberous sclerosis 1 protein antibody; tumor suppressor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92574 Immunogen:Recombinant Hamartin protein (101-344AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimµLated phosphorylation of S6K1 and EIF4EBP1 by negatively regµLating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubµLe-mediated protein transport, but this seems to be due to unregµLated mTOR signaling. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:TSC1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism