ELISA UFD1 anti-

Quantity :50µL Clone Number: Aliases:UB fusion protein 1 antibody; Ubiquitin fusion degradation 1 like (yeast) antibody; Ubiquitin fusion degradation 1 like antibody; Ubiquitin fusion degradation protein 1 homolog antibody; UFD1 antibody; UFD1_ antibody; UFD1L antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92890 Immunogen:Recombinant Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regµLates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:UFD1 Research Areas:Cell biology