ELISA SLC38A9 Antibody, HRP

Quantity :50µg Clone Number: Aliases:FLJ46104 antibody; FLJ90709 antibody; Homo sapiens solute carrier family 38; member 9 antibody; MGC120544 antibody; OTTHUMP00000161835 antibody; Putative sodium coupled neutral amino acid transporter 9 antibody; Putative sodium-coupled neutral amino acid transporter 9 antibody; Putative uncharacterized protein FLJ90709 antibody; S38A9_ antibody; SLC38A9 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8NBW4 Immunogen:Recombinant Sodium-coupled neutral amino acid transporter 9 protein (1-119AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and RagµLator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the RagµLator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, sµggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes sµggests that it acts as an arginine sensor (PubMed:25567906). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:SLC38A9 Research Areas:Metabolism; Signal transduction