ELISA RASGEF1A anti-

Quantity :50µL Clone Number: Aliases:CG4853 gene product antibody; Ras-GEF domain-containing family member 1A antibody; RasGEF domain family, member 1A antibody; rasgef1a antibody; RGF1A_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N9B8 Immunogen:Fusion protein of RASGEF1A Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:20-1:100 Background:RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RASGEF1A Research Areas:Cancer;Signal transduction